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Identification of MRTX1133, a Noncovalent, Potent, and Sele..:

Xiaolun Wang (2252662) ; Shelley Allen (1860448) ; James F. Blake (2039950)...
https://figshare.com/articles/journal_contribution/Identification_of_MRTX1133_a_Noncovalent_Potent_and_Selective_KRAS_sup_G12D_sup_Inhibitor/17159268. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c01688.s001

RT Journal
T1 <Title>Identification of MRTX1133, a Noncovalent, Potent, and Selective KRAS G12D Inhibitor</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17159268&Exemplar=1&LAN=DE
				
A1 Xiaolun Wang (2252662)
A1 Shelley Allen (1860448)
A1 James F. Blake (2039950)
A1 Vickie Bowcut (8408172)
A1 David M. Briere (5987522)
A1 Andrew Calinisan (8408166)
A1 Joshua R. Dahlke (11824182)
A1 Jay B. Fell (3022542)
A1 John P. Fischer (2983776)
A1 Robin J. Gunn (11824185)
A1 Jill Hallin (5987534)
A1 Jade Laguer (836370)
A1 J. David Lawson (1562440)
A1 James Medwid (11824188)
A1 Brad Newhouse (2201101)
A1 Phong Nguyen (694573)
A1 Jacob M. O'Leary (11824191)
A1 Peter Olson (824541)
A1 Spencer Pajk (11824194)
A1 Lisa Rahbaek (11134162)
A1 Mareli Rodriguez (11824197)
A1 Christopher R. Smith (1562425)
A1 Tony P. Tang (1845586)
A1 Nicole C. Thomas (1525276)
A1 Darin Vanderpool (2343520)
A1 Guy P. Vigers (5987549)
A1 James G. Christensen (156585)
A1 Matthew A. Marx (2134096)
YR 2021
K1 Biophysics
K1 Biochemistry
K1 Cell Biology
K1 Molecular Biology
K1 Pharmacology
K1 Biotechnology
K1 Cancer
K1 Hematology
K1 Infectious Diseases
K1 Chemical Sciences not elsewhere classified
K1 significant challenge due
K1 high enough affinity
K1 based activity improvement
K1 mutant kras protein
K1 g12d </ sup
K1 solid tumors
K1 selective kras
K1 promising target
K1 extensive structure
K1 covalent interactions
K1 bind kras
JF https://figshare.com/articles/journal_contribution/Identification_of_MRTX1133_a_Noncovalent_Potent_and_Selective_KRAS_sup_G12D_sup_Inhibitor/17159268
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01688.s001
DO https://doi.org/10.1021/acs.jmedchem.1c01688.s001
SF ELIB - SuUB Bremen

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