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Structure–Activity Studies of 3,9-Diazaspiro[5.5]undecane-B..:

Francesco Bavo (4059232) ; Heleen de-Jong (11840332) ; Jonas Petersen (5211479)...
https://figshare.com/articles/dataset/Structure_Activity_Studies_of_3_9-Diazaspiro_5_5_undecane-Based_Aminobutyric_Acid_Type_A_Receptor_Antagonists_with_Immunomodulatory_Effect/17207083. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c00290.s002

RT Journal
T1 <Title>Structure–Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based γ‑Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17207083&Exemplar=1&LAN=DE
				
A1 Francesco Bavo (4059232)
A1 Heleen de-Jong (11840332)
A1 Jonas Petersen (5211479)
A1 Christina Birkedahl Falk-Petersen (4578016)
A1 Rebekka Löffler (4522156)
A1 Emma Sparrow (11840335)
A1 Frederik Rostrup (10629947)
A1 Jannik Nicklas Eliasen (11840338)
A1 Kristine S. Wilhelmsen (11429440)
A1 Kasper Barslund (11840341)
A1 Christoffer Bundgaard (582285)
A1 Birgitte Nielsen (1399132)
A1 Uffe Kristiansen (1992253)
A1 Petrine Wellendorph (1530544)
A1 Yury Bogdanov (11840344)
A1 Bente Frølund (1530550)
YR 2021
K1 Biophysics
K1 Biochemistry
K1 Cell Biology
K1 Pharmacology
K1 Biotechnology
K1 Immunology
K1 Environmental Sciences not elsewhere classified
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 βδ subtype versus
K1 promising lead structures
K1 potent competitive γ
K1 nanomolar range (<
K1 displayed binding affinity
K1 conventional acidic moiety
K1 aminobutyric acid type
K1 >- methylphenyl analog
K1 potential binding mode
K1 emerging peripheral application
K1 efficiently rescue inhibition
K1 2027 </ b
K1 1e </ b
K1 018 </ b
K1 4 </ sub
K1 5 ] undecane
K1 immunomodulatory potential
K1 k </
K1 </ sub
K1 r inhibition
K1 structurally simplified
K1 structural determinants
K1 spirocyclic benzamide
K1 regarding selectivity
K1 rational design
K1 peripheral gaba
K1 immunomodulatory effect
K1 herein report
K1 cell proliferation
K1 >< sub
K1 180 nm
JF https://figshare.com/articles/dataset/Structure_Activity_Studies_of_3_9-Diazaspiro_5_5_undecane-Based_Aminobutyric_Acid_Type_A_Receptor_Antagonists_with_Immunomodulatory_Effect/17207083
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c00290.s002
DO https://doi.org/10.1021/acs.jmedchem.1c00290.s002
SF ELIB - SuUB Bremen

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