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Optimization of TAM16, a Benzofuran That Inhibits the Thioe..:

Caroline Wilson (1900477) ; Peter Ray (2866661) ; Fabio Zuccotto (1533349)...
https://figshare.com/articles/journal_contribution/Optimization_of_TAM16_a_Benzofuran_That_Inhibits_the_Thioesterase_Activity_of_Pks13_Evaluation_toward_a_Preclinical_Candidate_for_a_Novel_Antituberculosis_Clinical_Target/17209257. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c01586.s001

RT Journal
T1 <Title>Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17209257&Exemplar=1&LAN=DE
				
A1 Caroline Wilson (1900477)
A1 Peter Ray (2866661)
A1 Fabio Zuccotto (1533349)
A1 Jorge Hernandez (372146)
A1 Anup Aggarwal (11841432)
A1 Claire Mackenzie (473656)
A1 Nicola Caldwell (1622143)
A1 Malcolm Taylor (449567)
A1 Margaret Huggett (3223080)
A1 Michael Mathieson (9981299)
A1 Dinakaran Murugesan (1294683)
A1 Alasdair Smith (5562197)
A1 Susan Davis (3395426)
A1 Mattia Cocco (1697905)
A1 Maloy K. Parai (2074600)
A1 Arjun Acharya (1393660)
A1 Fabio Tamaki (11841435)
A1 Paul Scullion (1346427)
A1 Ola Epemolu (3012306)
A1 Jennifer Riley (309910)
A1 Laste Stojanovski (1282575)
A1 Eva Maria Lopez-Román (11841438)
A1 Pedro Alfonso Torres-Gómez (8732589)
A1 Ana Maria Toledo (11841441)
A1 Laura Guijarro-Lopez (11841444)
A1 Isabel Camino (7494527)
A1 Curtis A. Engelhart (1976239)
A1 Dirk Schnappinger (7052)
A1 Lisa M. Massoudi (11306138)
A1 Anne Lenaerts (401466)
A1 Gregory T. Robertson (1720168)
A1 Chris Walpole (3348356)
A1 David Matthews (1324497)
A1 David Floyd (2177010)
A1 James C. Sacchettini (37661)
A1 Kevin D. Read (165019)
A1 Lourdes Encinas (1684366)
A1 Robert H. Bates (380592)
A1 Simon R. Green (5006501)
A1 Paul G. Wyatt (473658)
YR 2021
K1 Biochemistry
K1 Medicine
K1 Pharmacology
K1 Biotechnology
K1 Infectious Diseases
K1 Space Science
K1 Environmental Sciences not elsewhere classified
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 Information Systems not elsewhere classified
K1 preexisting clinical resistance
K1 insufficient safety window
K1 increasing drug resistance
K1 multiple series members
K1 1 </ b
K1 attractive novel target
K1 novel target
K1 series toward
K1 series development
K1 novel targets
K1 vivo activity
K1 urgent need
K1 thioesterase domain
K1 thioesterase activity
K1 supports development
K1 promising activity
K1 preclinical candidate
K1 potential lead
K1 patient populations
K1 new drugs
K1 new compounds
K1 new agents
K1 main liability
K1 herg liability
K1 evaluation toward
K1 despite improvements
K1 current treatments
K1 concerns around
K1 article describes
K1 antitubercular drugs
K1 alternative chemotypes
JF https://figshare.com/articles/journal_contribution/Optimization_of_TAM16_a_Benzofuran_That_Inhibits_the_Thioesterase_Activity_of_Pks13_Evaluation_toward_a_Preclinical_Candidate_for_a_Novel_Antituberculosis_Clinical_Target/17209257
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01586.s001
DO https://doi.org/10.1021/acs.jmedchem.1c01586.s001
SF ELIB - SuUB Bremen

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