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1 Ergebnisse
1
Discovery of Dual CDK6/PIM1 Inhibitors with a Novel Structu..:
Kai Yuan (289810)
;
Minghui Ji (11879571)
;
Shengnan Xie (9970522)
...
https://figshare.com/articles/journal_contribution/Discovery_of_Dual_CDK6_PIM1_Inhibitors_with_a_Novel_Structure_High_Potency_and_Favorable_Druggability_for_the_Treatment_of_Acute_Myeloid_Leukemia/17695128. , 2021
Link:
https://doi.org/10.1021/acs.jmedchem.1c02019.s001
RT Journal T1
Discovery of Dual CDK6/PIM1 Inhibitors with a Novel Structure, High Potency, and Favorable Druggability for the Treatment of Acute Myeloid Leukemia
UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17695128&Exemplar=1&LAN=DE A1 Kai Yuan (289810) A1 Minghui Ji (11879571) A1 Shengnan Xie (9970522) A1 Zhixia Qiu (5535824) A1 Weijiao Chen (11879574) A1 Wenjian Min (11560191) A1 Fei Xia (256985) A1 Mingming Zheng (718716) A1 Xiao Wang (19312) A1 Jiaxing Li (113609) A1 Yi Hou (148620) A1 Wenbin Kuang (1404673) A1 Liping Wang (33601) A1 Wanjian Gu (8306460) A1 Zhiyu Li (10983) A1 Peng Yang (296696) YR 2021 K1 Biochemistry K1 Cell Biology K1 Pharmacology K1 Biotechnology K1 Cancer K1 Hematology K1 Infectious Diseases K1 Space Science K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 increasingly important role K1 great pharmacokinetic properties K1 generate synergistic effects K1 excellent safety profile K1 dependent kinase 6 K1 acute myeloid leukemia K1 great lead compound K1 based virtual screening K1 aml preclinical studies K1 51 </ b K1 1 </ b K1 displayed stronger potency K1 balanced dual cdk6 K1 cancer treatment due K1 vivo </ K1 via </ K1 novel lead K1 high potency K1 dual cdk6 K1 targeting cdk6 K1 simultaneous inhibition K1 pathways plays K1 new direction K1 new derivates K1 favorable druggability K1 diverse pathogenesis K1 aml treatment JF https://figshare.com/articles/journal_contribution/Discovery_of_Dual_CDK6_PIM1_Inhibitors_with_a_Novel_Structure_High_Potency_and_Favorable_Druggability_for_the_Treatment_of_Acute_Myeloid_Leukemia/17695128 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c02019.s001 DO https://doi.org/10.1021/acs.jmedchem.1c02019.s001 SF ELIB - SuUB Bremen
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