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Discovery of Dual CDK6/PIM1 Inhibitors with a Novel Structu..:

Kai Yuan (289810) ; Minghui Ji (11879571) ; Shengnan Xie (9970522)...
https://figshare.com/articles/dataset/Discovery_of_Dual_CDK6_PIM1_Inhibitors_with_a_Novel_Structure_High_Potency_and_Favorable_Druggability_for_the_Treatment_of_Acute_Myeloid_Leukemia/17695134. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c02019.s003

RT Journal
T1 <Title>Discovery of Dual CDK6/PIM1 Inhibitors with a Novel Structure, High Potency, and Favorable Druggability for the Treatment of Acute Myeloid Leukemia</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17695134&Exemplar=1&LAN=DE
				
A1 Kai Yuan (289810)
A1 Minghui Ji (11879571)
A1 Shengnan Xie (9970522)
A1 Zhixia Qiu (5535824)
A1 Weijiao Chen (11879574)
A1 Wenjian Min (11560191)
A1 Fei Xia (256985)
A1 Mingming Zheng (718716)
A1 Xiao Wang (19312)
A1 Jiaxing Li (113609)
A1 Yi Hou (148620)
A1 Wenbin Kuang (1404673)
A1 Liping Wang (33601)
A1 Wanjian Gu (8306460)
A1 Zhiyu Li (10983)
A1 Peng Yang (296696)
YR 2021
K1 Biochemistry
K1 Cell Biology
K1 Pharmacology
K1 Biotechnology
K1 Cancer
K1 Hematology
K1 Infectious Diseases
K1 Space Science
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 increasingly important role
K1 great pharmacokinetic properties
K1 generate synergistic effects
K1 excellent safety profile
K1 dependent kinase 6
K1 acute myeloid leukemia
K1 great lead compound
K1 based virtual screening
K1 aml preclinical studies
K1 51 </ b
K1 1 </ b
K1 displayed stronger potency
K1 balanced dual cdk6
K1 cancer treatment due
K1 vivo </
K1 via </
K1 novel lead
K1 high potency
K1 dual cdk6
K1 targeting cdk6
K1 simultaneous inhibition
K1 pathways plays
K1 new direction
K1 new derivates
K1 favorable druggability
K1 diverse pathogenesis
K1 aml treatment
JF https://figshare.com/articles/dataset/Discovery_of_Dual_CDK6_PIM1_Inhibitors_with_a_Novel_Structure_High_Potency_and_Favorable_Druggability_for_the_Treatment_of_Acute_Myeloid_Leukemia/17695134
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c02019.s003
DO https://doi.org/10.1021/acs.jmedchem.1c02019.s003
SF ELIB - SuUB Bremen

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