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Structure-Guided Discovery of Aminoquinazolines as Brain-Pe..:

Mitchell H. Keylor (8615976) ; Anmol Gulati (1314951) ; Solomon D. Kattar (11888244)...
https://figshare.com/articles/journal_contribution/Structure-Guided_Discovery_of_Aminoquinazolines_as_Brain-Penetrant_and_Selective_LRRK2_Inhibitors/17705925. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c01968.s002

RT Journal
T1 <Title>Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17705925&Exemplar=1&LAN=DE
				
A1 Mitchell H. Keylor (8615976)
A1 Anmol Gulati (1314951)
A1 Solomon D. Kattar (11888244)
A1 Rebecca E. Johnson (1361724)
A1 Ryan W. Chau (11888247)
A1 Kaila A. Margrey (1849126)
A1 Michael J. Ardolino (2154361)
A1 Cayetana Zarate (1516576)
A1 Kelsey E. Poremba (3903853)
A1 Vladimir Simov (2534833)
A1 Gregori J. Morriello (2645770)
A1 John J. Acton (11888250)
A1 Barbara Pio (1601539)
A1 Xin Yan (17064)
A1 Rachel L. Palte (8299626)
A1 Spencer E. McMinn (9931798)
A1 Lisa Nogle (2160265)
A1 Charles A. Lesburg (1834624)
A1 Donovon Adpressa (8448369)
A1 Shishi Lin (752964)
A1 Santhosh Neelamkavil (2679916)
A1 Ping Liu (156158)
A1 Jing Su (23377)
A1 Laxminarayan G. Hegde (2480896)
A1 Janice D. Woodhouse (8299629)
A1 Robert Faltus (11888253)
A1 Tina Xiong (6095357)
A1 Paul J. Ciaccio (11888256)
A1 Jennifer Piesvaux (5987792)
A1 Karin M. Otte (2459014)
A1 Harold B. Wood (1665394)
A1 Matthew E. Kennedy (2026285)
A1 David Jonathan Bennett (7456754)
A1 Erin F. DiMauro (797168)
A1 Matthew J. Fell (3839692)
A1 Peter H. Fuller (2400580)
YR 2021
K1 Biochemistry
K1 Medicine
K1 Genetics
K1 Neuroscience
K1 Pharmacology
K1 Biotechnology
K1 Evolutionary Biology
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 Information Systems not elsewhere classified
K1 stereochemical design elements
K1 hydrogen bond donor
K1 friendly profile typified
K1 central nervous system
K1 selective lrrk2 inhibitors
K1 encouraging brain penetration
K1 22 </ b
K1 structural enablement
K1 rigorous hit
K1 quality molecules
K1 preclinical models
K1 pd )
K1 parkinson '
K1 mediated efflux
K1 low levels
K1 functionally linked
K1 enhancing increase
JF https://figshare.com/articles/journal_contribution/Structure-Guided_Discovery_of_Aminoquinazolines_as_Brain-Penetrant_and_Selective_LRRK2_Inhibitors/17705925
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01968.s002
DO https://doi.org/10.1021/acs.jmedchem.1c01968.s002
SF ELIB - SuUB Bremen

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