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1 Ergebnisse
1
Structure-Based Design and Biological Evaluation of Novel C..:
Merlin Bresinsky (10954861)
;
Jessica M. Strasser (486124)
;
Bernadette Vallaster (11908633)
...
https://figshare.com/articles/dataset/Structure-Based_Design_and_Biological_Evaluation_of_Novel_Caspase_2_Inhibitors_Based_on_the_Peptide_AcVDVAD-CHO_and_the_Caspase-2-Mediated_Tau_Cleavage_Sequence_YKPVD314/17884966. , 2022
Link:
https://doi.org/10.1021/acsptsci.1c00251.s002
RT Journal T1
Structure-Based Design and Biological Evaluation of Novel Caspase‑2 Inhibitors Based on the Peptide AcVDVAD-CHO and the Caspase-2-Mediated Tau Cleavage Sequence YKPVD314
UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17884966&Exemplar=1&LAN=DE A1 Merlin Bresinsky (10954861) A1 Jessica M. Strasser (486124) A1 Bernadette Vallaster (11908633) A1 Peng Liu (120506) A1 William M. McCue (11908636) A1 Jessica Fuller (11908639) A1 Alexander Hubmann (11908642) A1 Gurpreet Singh (1291665) A1 Kathryn M. Nelson (2032519) A1 Matthew E. Cuellar (6424661) A1 Carrie M. Wilmot (1864492) A1 Barry C. Finzel (1484449) A1 Karen H. Ashe (11908645) A1 Michael A. Walters (486126) A1 Steffen Pockes (1831753) YR 2022 K1 Biochemistry K1 Molecular Biology K1 Neuroscience K1 Pharmacology K1 Cancer K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 reversibly impairs cognitive K1 mediated cleavage product K1 like small molecules K1 100 years ago K1 simple peptidic inhibitors K1 35 pentapeptide inhibitors K1 vitro cleavage assay K1 recombinant tau mutants K1 cho (< b K1 casp2 binding site K1 selective casp2 probes K1 vivo studies K1 treat either K1 synaptic function K1 studies resulted K1 selective caspase K1 selected pentapeptides K1 potential approach K1 pharmacological tools K1 peptide acvdvad K1 overarching theory K1 nanomolar affinity K1 lead compounds K1 key interactions K1 good basis K1 gaining selectivity K1 fold selectivity K1 first described K1 findings provide K1 effective therapies K1 differences predicted K1 crystallographically characterized K1 biological evaluation K1 binding pocket K1 associated symptoms K1 animal models K1 alois alzheimer JF https://figshare.com/articles/dataset/Structure-Based_Design_and_Biological_Evaluation_of_Novel_Caspase_2_Inhibitors_Based_on_the_Peptide_AcVDVAD-CHO_and_the_Caspase-2-Mediated_Tau_Cleavage_Sequence_YKPVD314/17884966 LK http://dx.doi.org/https://doi.org/10.1021/acsptsci.1c00251.s002 DO https://doi.org/10.1021/acsptsci.1c00251.s002 SF ELIB - SuUB Bremen
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