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Structure-Based Design and Biological Evaluation of Novel C..:

Merlin Bresinsky (10954861) ; Jessica M. Strasser (486124) ; Bernadette Vallaster (11908633)...
https://figshare.com/articles/dataset/Structure-Based_Design_and_Biological_Evaluation_of_Novel_Caspase_2_Inhibitors_Based_on_the_Peptide_AcVDVAD-CHO_and_the_Caspase-2-Mediated_Tau_Cleavage_Sequence_YKPVD314/17884966. , 2022

Link: https://doi.org/10.1021/acsptsci.1c00251.s002

RT Journal
T1 <Title>Structure-Based Design and Biological Evaluation of Novel Caspase‑2 Inhibitors Based on the Peptide AcVDVAD-CHO and the Caspase-2-Mediated Tau Cleavage Sequence YKPVD314</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17884966&Exemplar=1&LAN=DE
				
A1 Merlin Bresinsky (10954861)
A1 Jessica M. Strasser (486124)
A1 Bernadette Vallaster (11908633)
A1 Peng Liu (120506)
A1 William M. McCue (11908636)
A1 Jessica Fuller (11908639)
A1 Alexander Hubmann (11908642)
A1 Gurpreet Singh (1291665)
A1 Kathryn M. Nelson (2032519)
A1 Matthew E. Cuellar (6424661)
A1 Carrie M. Wilmot (1864492)
A1 Barry C. Finzel (1484449)
A1 Karen H. Ashe (11908645)
A1 Michael A. Walters (486126)
A1 Steffen Pockes (1831753)
YR 2022
K1 Biochemistry
K1 Molecular Biology
K1 Neuroscience
K1 Pharmacology
K1 Cancer
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 reversibly impairs cognitive
K1 mediated cleavage product
K1 like small molecules
K1 100 years ago
K1 simple peptidic inhibitors
K1 35 pentapeptide inhibitors
K1 vitro cleavage assay
K1 recombinant tau mutants
K1 cho (< b
K1 casp2 binding site
K1 selective casp2 probes
K1 vivo studies
K1 treat either
K1 synaptic function
K1 studies resulted
K1 selective caspase
K1 selected pentapeptides
K1 potential approach
K1 pharmacological tools
K1 peptide acvdvad
K1 overarching theory
K1 nanomolar affinity
K1 lead compounds
K1 key interactions
K1 good basis
K1 gaining selectivity
K1 fold selectivity
K1 first described
K1 findings provide
K1 effective therapies
K1 differences predicted
K1 crystallographically characterized
K1 biological evaluation
K1 binding pocket
K1 associated symptoms
K1 animal models
K1 alois alzheimer
JF https://figshare.com/articles/dataset/Structure-Based_Design_and_Biological_Evaluation_of_Novel_Caspase_2_Inhibitors_Based_on_the_Peptide_AcVDVAD-CHO_and_the_Caspase-2-Mediated_Tau_Cleavage_Sequence_YKPVD314/17884966
LK http://dx.doi.org/https://doi.org/10.1021/acsptsci.1c00251.s002
DO https://doi.org/10.1021/acsptsci.1c00251.s002
SF ELIB - SuUB Bremen

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