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Design of a Potent TLX Agonist by Rational Fragment Fusion:

Giuseppe Faudone (8735997) ; Rezart Zhubi (10961545) ; Fatih Celik (5228297)...
https://figshare.com/articles/journal_contribution/Design_of_a_Potent_TLX_Agonist_by_Rational_Fragment_Fusion/17942276. , 2022

Link: https://doi.org/10.1021/acs.jmedchem.1c01757.s001

RT Journal
T1 <Title>Design of a Potent TLX Agonist by Rational Fragment Fusion</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17942276&Exemplar=1&LAN=DE
				
A1 Giuseppe Faudone (8735997)
A1 Rezart Zhubi (10961545)
A1 Fatih Celik (5228297)
A1 Stefan Knapp (244328)
A1 Apirat Chaikuad (244322)
A1 Jan Heering (1373691)
A1 Daniel Merk (1373682)
YR 2022
K1 Biophysics
K1 Biochemistry
K1 Cell Biology
K1 Genetics
K1 Molecular Biology
K1 Neuroscience
K1 Pharmacology
K1 Biotechnology
K1 Immunology
K1 Chemical Sciences not elsewhere classified
K1 tumor suppressor genes
K1 related nuclear receptors
K1 potent tlx modulators
K1 potent tlx agonist
K1 10 </ b
K1 fragment screening hit
K1 rational fragment fusion
K1 fragment screening
K1 fragment fusion
K1 rational basis
K1 fragment linkage
K1 transcriptional repressor
K1 submicromolar potency
K1 promising potential
K1 pharmacophore similarity
K1 pharmacophore modeling
K1 neurodegenerative diseases
K1 master regulator
K1 high selectivity
K1 hence considered
K1 fused compound
K1 functional studies
K1 appealing target
JF https://figshare.com/articles/journal_contribution/Design_of_a_Potent_TLX_Agonist_by_Rational_Fragment_Fusion/17942276
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01757.s001
DO https://doi.org/10.1021/acs.jmedchem.1c01757.s001
SF ELIB - SuUB Bremen

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