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1 Ergebnisse
1
Design, Synthesis, and Characterization of I‑BET567, a Pan-..:
Philip G. Humphreys (1357530)
;
Stephen J. Atkinson (1297362)
;
Paul Bamborough (1343466)
...
https://figshare.com/articles/journal_contribution/Design_Synthesis_and_Characterization_of_I_BET567_a_Pan-Bromodomain_and_Extra_Terminal_BET_Bromodomain_Oral_Candidate/18064456. , 1753
Link:
https://doi.org/10.1021/acs.jmedchem.1c01747.s001
RT Journal T1
Design, Synthesis, and Characterization of I‑BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate
UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_18064456&Exemplar=1&LAN=DE A1 Philip G. Humphreys (1357530) A1 Stephen J. Atkinson (1297362) A1 Paul Bamborough (1343466) A1 Rino A. Bit (1357536) A1 Chun-wa Chung (1343454) A1 Peter D. Craggs (7180412) A1 Leanne Cutler (1738141) A1 Rob Davis (9204195) A1 Alan Ferrie (11920186) A1 GangLi Gong (11920189) A1 Laurie J. Gordon (1343442) A1 Matthew Gray (2402251) A1 Lee A. Harrison (2160145) A1 Thomas G. Hayhow (3624884) A1 Andrea Haynes (1399255) A1 Nick Henley (11920192) A1 David J. Hirst (1399282) A1 Ian D. Holyer (11920195) A1 Matthew J. Lindon (8232792) A1 Cerys Lovatt (11920198) A1 David Lugo (2803279) A1 Scott McCleary (8232795) A1 Judit Molnar (1357521) A1 Qendresa Osmani (11920201) A1 Chris Patten (8232804) A1 Alex Preston (9105252) A1 Inmaculada Rioja (8539) A1 Jonathan T. Seal (2119816) A1 Nicholas Smithers (487233) A1 Fenglai Sun (11920204) A1 Dalin Tang (835554) A1 Simon Taylor (441637) A1 Natalie H. Theodoulou (1508650) A1 Clare Thomas (7943747) A1 Robert J. Watson (1343463) A1 Christopher R. Wellaway (7148462) A1 Linrong Zhu (11920207) A1 Nicholas C. O. Tomkinson (7417448) A1 Rab K. Prinjha (449759) YR 1753 K1 Biochemistry K1 Medicine K1 Molecular Biology K1 Pharmacology K1 Biotechnology K1 Sociology K1 Immunology K1 Hematology K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 potency agnostic analysis K1 orally bioavailable tetrahydroquinoline K1 medicinal chemistry strategy K1 bet567 (< b K1 appropriate lipophilicity space K1 oncology clinical trials K1 bromodomain oral candidate K1 bet candidate inhibitor K1 bet candidate K1 ‑ bet567 K1 work describes K1 ultimately delivered K1 small group K1 sar knowledge K1 n </ K1 mouse models K1 lysine group K1 human disease K1 histone tails K1 higher probability K1 gsk collection K1 extra terminal K1 enabled identification K1 design space K1 demonstrated efficacy K1 data set K1 bet inhibitors K1 >- acetyl JF https://figshare.com/articles/journal_contribution/Design_Synthesis_and_Characterization_of_I_BET567_a_Pan-Bromodomain_and_Extra_Terminal_BET_Bromodomain_Oral_Candidate/18064456 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01747.s001 DO https://doi.org/10.1021/acs.jmedchem.1c01747.s001 SF ELIB - SuUB Bremen
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