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Engineering of a T7 Bacteriophage Endolysin Variant with En..:

Jaya Lakshmi Tyagi (6081314) ; Meenakshi Sharma (107997) ; Khushboo Gulati (4400101)...
https://figshare.com/articles/journal_contribution/Engineering_of_a_T7_Bacteriophage_Endolysin_Variant_with_Enhanced_Amidase_Activity/18858101. , 1753

Link: https://doi.org/10.1021/acs.biochem.1c00710.s001

RT Journal
T1 <Title>Engineering of a T7 Bacteriophage Endolysin Variant with Enhanced Amidase Activity</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_18858101&Exemplar=1&LAN=DE
				
A1 Jaya Lakshmi Tyagi (6081314)
A1 Meenakshi Sharma (107997)
A1 Khushboo Gulati (4400101)
A1 Manikyaprabhu Kairamkonda (11984252)
A1 Dinesh Kumar (81794)
A1 Krishna Mohan Poluri (7498073)
YR 1753
K1 Biophysics
K1 Biochemistry
K1 Pharmacology
K1 Biotechnology
K1 thus aiding researchers
K1 recent years due
K1 range structural perturbations
K1 provide mechanistic insights
K1 obtained results established
K1 noncatalytic gating residue
K1 guided mutagenesis approach
K1 type t7 endolysin
K1 two h37 variants
K1 stability analysis confirmed
K1 enhanced amidase activity
K1 phage endolysins lyse
K1 enhanced therapeutic properties
K1 various engineering strategies
K1 antibiotic resistant bacteria
K1 t7 bacteriophage endolysin
K1 h37a variant enhances
K1 endolysin proteins
K1 lysis activity
K1 h37 resulted
K1 altered stability
K1 therapeutic use
K1 therapeutic enzymes
K1 h37a variant
K1 engineered endolysins
K1 encoded endolysins
K1 wt evidenced
K1 wt counterpart
K1 wt )
K1 study employed
K1 studied proteins
K1 rational design
K1 less active
K1 increased significantly
K1 highly unstable
K1 h37a compared
K1 conformational heterogeneity
K1 commonly used
K1 cell wall
K1 biochemical techniques
K1 37 )
JF https://figshare.com/articles/journal_contribution/Engineering_of_a_T7_Bacteriophage_Endolysin_Variant_with_Enhanced_Amidase_Activity/18858101
LK http://dx.doi.org/https://doi.org/10.1021/acs.biochem.1c00710.s001
DO https://doi.org/10.1021/acs.biochem.1c00710.s001
SF ELIB - SuUB Bremen

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