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Negative DNA supercoiling induces genome-wide Cas9 off-targ..:

Newton, MD ; Losito, M ; Smith, QM...
https://discovery.ucl.ac.uk/id/eprint/10178647/1/King_Negative%20DNA%20supercoiling%20induces%20genome-wide%20Cas9%20off-target%20activity_VoR.pdf. , 2023

Link: https://discovery.ucl.ac.uk/id/eprint/10178647/1/King_..

RT Journal
T1 <Title>Negative DNA supercoiling induces genome-wide Cas9 off-target activity</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftucl:oai:eprints.ucl.ac.uk.OAI2:10178647&Exemplar=1&LAN=DE
				
A1 Newton, MD
A1 Losito, M
A1 Smith, QM
A1 Parnandi, N
A1 Taylor, BJ
A1 Akcakaya, P
A1 Maresca, M
A1 van Eijk, P
A1 Reed, SH
A1 Boulton, SJ
A1 King, GA
A1 Cuomo, ME
A1 Rueda, DS
PB Elsevier BV
YR 2023
K1 CRISPR/Cas9
K1 Gene editing
K1 DNA topology
K1 Genome-wide off-target
K1 Single-molecule microscopy
K1 Optical-tweezers
K1 Negative supercoiling
K1 Next Generation Sequencing
K1 Cell editing
K1 Transcription-coupled off-targets
JF https://discovery.ucl.ac.uk/id/eprint/10178647/1/King_Negative%20DNA%20supercoiling%20induces%20genome-wide%20Cas9%20off-target%20activity_VoR.pdf
LK http://dx.doi.org/https://discovery.ucl.ac.uk/id/eprint/10178647/1/King_Negative%20DNA%20supercoiling%20induces%20genome-wide%20Cas9%20off-target%20activity_VoR.pdf
DO https://discovery.ucl.ac.uk/id/eprint/10178647/1/King_Negative%20DNA%20supercoiling%20induces%20genome-wide%20Cas9%20off-target%20activity_VoR.pdf
SF ELIB - SuUB Bremen

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