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The impact of thioredoxin reduction of allosteric disulfide..:

Gurjar, Shalom A ; Wheeler, Jun X ; Wadwha, Meenu...
Gurjar , S A , Wheeler , J X , Wadwha , M , Thorpe , R , Kimber , I , Derrick , J , Dearman , R & Metcalfe , C 2019 , ' The impact of thioredoxin reduction of allosteric disulfide bonds on the therapeutic potential of monoclonal antibodies ' , Journal of Biological Chemistry , vol. 294 , no. 51 , pp. 19616-19634 . https://doi.org/10.1074/jbc.RA119.010637. , 2019

Link: https://research.manchester.ac.uk/en/publications/b1af..

RT Journal
T1 <Title>The impact of thioredoxin reduction of allosteric disulfide bonds on the therapeutic potential of monoclonal antibodies</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftumanchesterpub:oai:pure.atira.dk:publications_b1afd3ca-16f1-4cff-9efb-d2f7606efadd&Exemplar=1&LAN=DE
				
A1 Gurjar, Shalom A
A1 Wheeler, Jun X
A1 Wadwha, Meenu
A1 Thorpe, Robin
A1 Kimber, Ian
A1 Derrick, Jeremy
A1 Dearman, Rebecca
A1 Metcalfe, Clive
YR 2019
K1 allosteric regulation
K1 thioredoxin (Trx)
K1 monoclonal antibody
K1 redox regulation
K1 antibody-dependent cellular cytotoxicity (ADCC)
K1 complement-dependent cytotoxicity (CDC)
JF Gurjar , S A , Wheeler , J X , Wadwha , M , Thorpe , R , Kimber , I , Derrick , J , Dearman , R & Metcalfe , C 2019 , ' The impact of thioredoxin reduction of allosteric disulfide bonds on the therapeutic potential of monoclonal antibodies ' , Journal of Biological Chemistry , vol. 294 , no. 51 , pp. 19616-19634 . https://doi.org/10.1074/jbc.RA119.010637
LK http://dx.doi.org/https://research.manchester.ac.uk/en/publications/b1afd3ca-16f1-4cff-9efb-d2f7606efadd
DO https://research.manchester.ac.uk/en/publications/b1afd3ca-16f1-4cff-9efb-d2f7606efadd
SF ELIB - SuUB Bremen

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