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Discovery of a Series of Potent, Selective, and Orally Bioa..:

Jim Li (1833814) ; Lijing Chen (142877) ; Roland J. Billedeau (1973452)...
https://figshare.com/articles/journal_contribution/Discovery_of_a_Series_of_Potent_Selective_and_Orally_Bioavailable_Nucleoside_Inhibitors_of_CD73_That_Demonstrates_i_In_Vivo_i_Antitumor_Activity/21749301. , 1753

Link: https://doi.org/10.1021/acs.jmedchem.2c01287.s002

RT Journal
T1 <Title>Discovery of a Series of Potent, Selective, and Orally Bioavailable Nucleoside Inhibitors of CD73 That Demonstrates In Vivo Antitumor Activity</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftunivfreestate:oai:figshare.com:article_21749301&Exemplar=1&LAN=DE
				
A1 Jim Li (1833814)
A1 Lijing Chen (142877)
A1 Roland J. Billedeau (1973452)
A1 Timothy F. Stanton (14277315)
A1 John T. P. Chiang (14277318)
A1 Clarissa C. Lee (14277321)
A1 Weiqun Li (8297628)
A1 Susanne Steggerda (14277324)
A1 Ethan Emberley (11642767)
A1 Matthew Gross (186853)
A1 Deepthi Bhupathi (2219005)
A1 Xiaoying Che (14277327)
A1 Jason Chen (15937)
A1 Rosalyn Dang (11642770)
A1 Tony Huang (6483005)
A1 Yong Ma (381691)
A1 Andrew MacKinnon (3448271)
A1 Amani Makkouk (14277330)
A1 Gisele Marguier (14277333)
A1 Silinda Neou (14277336)
A1 Natalija Sotirovska (11642779)
A1 Sandra Spurlock (14277339)
A1 Jing Zhang (23775)
A1 Winter Zhang (14277342)
A1 Michael van Zandt (14277345)
A1 Lin Yuan (46306)
A1 Jennifer Savoy (7305953)
A1 Francesco Parlati (1261995)
A1 Eric B. Sjogren (2209540)
YR 1753
K1 Biochemistry
K1 Cell Biology
K1 Molecular Biology
K1 Pharmacology
K1 Biotechnology
K1 Immunology
K1 Cancer
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 sup >+</ sup
K1 5 ′- nucleotidase
K1 reported hit molecule
K1 various cancer patients
K1 mouse tumor model
K1 mediated antitumor mechanism
K1 highly immunosuppressive adenosine
K1 developing orally bioavailable
K1 antitumor activity cd73
K1 49 </ b
K1 20 </ b
K1 2 </ b
K1 highly potent small
K1 molecule cd73 inhibitors
K1 vivo </
K1 lead molecule
K1 tumor progression
K1 orally administered
K1 mediated suppression
K1 cancer immunotherapy
K1 adenosine monophosphate
K1 cd73 catalyzes
K1 single agent
K1 serum samples
K1 robust dose
K1 many cancers
K1 expected immune
K1 either chemotherapeutics
K1 dependent pharmacokinetic
K1 critical role
K1 checkpoint inhibitor
K1 attractive target
JF https://figshare.com/articles/journal_contribution/Discovery_of_a_Series_of_Potent_Selective_and_Orally_Bioavailable_Nucleoside_Inhibitors_of_CD73_That_Demonstrates_i_In_Vivo_i_Antitumor_Activity/21749301
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.2c01287.s002
DO https://doi.org/10.1021/acs.jmedchem.2c01287.s002
SF ELIB - SuUB Bremen

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