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Structure-Based Design of the Indole-Substituted Triazolopy..:

Guanjun Dong (5966684) ; Jiahui Zuo (10119146) ; Junlin Yu (8358930)...
https://figshare.com/articles/dataset/Structure-Based_Design_of_the_Indole-Substituted_Triazolopyrimidines_as_New_EED_H3K27me3_Inhibitors_for_the_Treatment_of_Lymphoma/21790104. , 2022

Link: https://doi.org/10.1021/acs.jmedchem.2c02028.s003

RT Journal
T1 <Title>Structure-Based Design of the Indole-Substituted Triazolopyrimidines as New EED–H3K27me3 Inhibitors for the Treatment of Lymphoma</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftunivfreestate:oai:figshare.com:article_21790104&Exemplar=1&LAN=DE
				
A1 Guanjun Dong (5966684)
A1 Jiahui Zuo (10119146)
A1 Junlin Yu (8358930)
A1 Jiale Xu (1882273)
A1 Ge Gao (5909)
A1 Guo-Bo Li (1600735)
A1 Wen Zhao (302324)
A1 Bin Yu (14464)
YR 2022
K1 Biochemistry
K1 Microbiology
K1 Genetics
K1 Molecular Biology
K1 Pharmacology
K1 Biotechnology
K1 Developmental Biology
K1 Cancer
K1 Hematology
K1 Infectious Diseases
K1 Plant Biology
K1 Chemical Sciences not elsewhere classified
K1 robust antitumor efficacy
K1 gene silencing function
K1 embryonic ectoderm development
K1 advanced preclinical development
K1 rich indole ring
K1 karpas422 xenograft model
K1 16 directly binds
K1 based eed inhibitors
K1 50 </ sub
K1 favorable pk profiles
K1 based design
K1 k </
K1 f </
K1 </ sub
K1 substituted triazolopyrimidines
K1 structurally feature
K1 selectively engaged
K1 promising strategy
K1 potently inhibits
K1 oral administration
K1 new triazolopyrimidine
K1 lymphoma interrupting
K1 htrf ic
K1 cancer therapy
K1 c8 position
K1 >< sub
K1 72 nm
K1 7 %)
K1 16 warrant
K1 16 inhibits
JF https://figshare.com/articles/dataset/Structure-Based_Design_of_the_Indole-Substituted_Triazolopyrimidines_as_New_EED_H3K27me3_Inhibitors_for_the_Treatment_of_Lymphoma/21790104
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.2c02028.s003
DO https://doi.org/10.1021/acs.jmedchem.2c02028.s003
SF ELIB - SuUB Bremen

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