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Discovery of TP0597850: A Selective, Chemically Stable, and..:

Tomoki Takeuchi (1811875) ; Yusaku Nomura (12859997) ; Tomoko Tamita (12859994)...
https://figshare.com/articles/journal_contribution/Discovery_of_TP0597850_A_Selective_Chemically_Stable_and_Slow_Tight-Binding_Matrix_Metalloproteinase_2_Inhibitor_with_a_Phenylbenzamide_Pentapeptide_Hybrid_Scaffold/21807053. , 2023

Link: https://doi.org/10.1021/acs.jmedchem.2c01698.s001

RT Journal
T1 <Title>Discovery of TP0597850: A Selective, Chemically Stable, and Slow Tight-Binding Matrix Metalloproteinase‑2 Inhibitor with a Phenylbenzamide–Pentapeptide Hybrid Scaffold</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftunivfreestate:oai:figshare.com:article_21807053&Exemplar=1&LAN=DE
				
A1 Tomoki Takeuchi (1811875)
A1 Yusaku Nomura (12859997)
A1 Tomoko Tamita (12859994)
A1 Rie Nishikawa (2285410)
A1 Hiroyuki Kakinuma (12860012)
A1 Naoki Kojima (6736481)
A1 Kosuke Hitaka (8763999)
A1 Yunoshin Tamura (1788742)
A1 Masafumi Kamitani (12860003)
A1 Masashi Mima (8763990)
A1 Akiko Nozoe (12860009)
A1 Masato Hayashi (1903846)
YR 2023
K1 Biophysics
K1 Biochemistry
K1 Cell Biology
K1 Molecular Biology
K1 Pharmacology
K1 Biotechnology
K1 Evolutionary Biology
K1 Ecology
K1 Cancer
K1 Infectious Diseases
K1 Virology
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 s1 ′ pocket
K1 kinetic analysis revealed
K1 265 min )
K1 possesses slow tight
K1 high chemical stability
K1 tp0597850 (< b
K1 2 </ sub
K1 1 </ b
K1 slow tight
K1 chemical stability
K1 </ sub
K1 life (<
K1 glu )
K1 >< sub
K1 k </
K1 ≥ 2000
K1 wide range
K1 various diseases
K1 tripeptide linker
K1 shorter linker
K1 promising target
K1 ph values
K1 new generation
K1 inhibition constants
K1 including cancer
K1 dependent endopeptidase
K1 degradation mechanism
K1 chemically stable
K1 binding nature
K1 binding group
K1 binding features
K1 aminopentanoic acid
K1 034 nm
JF https://figshare.com/articles/journal_contribution/Discovery_of_TP0597850_A_Selective_Chemically_Stable_and_Slow_Tight-Binding_Matrix_Metalloproteinase_2_Inhibitor_with_a_Phenylbenzamide_Pentapeptide_Hybrid_Scaffold/21807053
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.2c01698.s001
DO https://doi.org/10.1021/acs.jmedchem.2c01698.s001
SF ELIB - SuUB Bremen

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