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Structural Alterations of the "Address" Moiety of NAN Leadi..:

Hongguang Ma (5105198) ; Piyusha P. Pagare (4433698) ; Mengchu Li (8108468)...
https://figshare.com/articles/dataset/Structural_Alterations_of_the_Address_Moiety_of_NAN_Leading_to_the_Discovery_of_a_Novel_Opioid_Receptor_Modulator_with_Reduced_hERG_Toxicity/21814391. , 2022

Link: https://doi.org/10.1021/acs.jmedchem.2c01499.s002

RT Journal
T1 <Title>Structural Alterations of the "Address" Moiety of NAN Leading to the Discovery of a Novel Opioid Receptor Modulator with Reduced hERG Toxicity</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftunivfreestate:oai:figshare.com:article_21814391&Exemplar=1&LAN=DE
				
A1 Hongguang Ma (5105198)
A1 Piyusha P. Pagare (4433698)
A1 Mengchu Li (8108468)
A1 Logan T. Neel (9927791)
A1 Rolando E. Mendez (12210748)
A1 James C. Gillespie (12210745)
A1 David L. Stevens (1878574)
A1 William L. Dewey (306219)
A1 Dana E. Selley (1448944)
A1 Yan Zhang (8098)
YR 2022
K1 Biophysics
K1 Biochemistry
K1 Medicine
K1 Genetics
K1 Neuroscience
K1 Pharmacology
K1 Biotechnology
K1 Infectious Diseases
K1 Space Science
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 substituted naltrexamine derivative
K1 significant human ether
K1 several fundamental drug
K1 selective opioid ligands
K1 reasonable adme profile
K1 promising opioid modulator
K1 previous effort yielded
K1 preserving pharmacological properties
K1 potent opioid modulator
K1 improved safety profile
K1 fold decreased potency
K1 desired pharmacological potency
K1 systematic structural modification
K1 reduced herg toxicity
K1 alleviate herg toxicity
K1 21 </ b
K1 structural alterations
K1 n </
K1 related gene
K1 liability limited
K1 6α -<
JF https://figshare.com/articles/dataset/Structural_Alterations_of_the_Address_Moiety_of_NAN_Leading_to_the_Discovery_of_a_Novel_Opioid_Receptor_Modulator_with_Reduced_hERG_Toxicity/21814391
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.2c01499.s002
DO https://doi.org/10.1021/acs.jmedchem.2c01499.s002
SF ELIB - SuUB Bremen

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