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Chemical Biology Approaches Confirm MCT4 as the Therapeutic..:

Aarti Kawatkar (5375711) ; Roger A. Clark (12300593) ; Lorna Hopcroft (14270985)...
https://figshare.com/articles/dataset/Chemical_Biology_Approaches_Confirm_MCT4_as_the_Therapeutic_Target_of_a_Cellular_Optimized_Hit/21821532. , 2023

Link: https://doi.org/10.1021/acschembio.2c00666.s003

RT Journal
T1 <Title>Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftunivfreestate:oai:figshare.com:article_21821532&Exemplar=1&LAN=DE
				
A1 Aarti Kawatkar (5375711)
A1 Roger A. Clark (12300593)
A1 Lorna Hopcroft (14270985)
A1 Debora Ann Roaquin (14332941)
A1 Ronald Tomlinson (14332944)
A1 Andrea M. Zuhl (2180184)
A1 Gillian M. Lamont (1763368)
A1 Jason G. Kettle (1398433)
A1 Susan E. Critchlow (1613527)
A1 M. Paola Castaldi (2358850)
A1 Frederick W. Goldberg (1845706)
A1 Andrew X. Zhang (1371321)
YR 2023
K1 Biophysics
K1 Biochemistry
K1 Microbiology
K1 Genetics
K1 Molecular Biology
K1 Pharmacology
K1 Biotechnology
K1 Cancer
K1 Inorganic Chemistry
K1 Hematology
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 Information Systems not elsewhere classified
K1 traditional biophysical methods
K1 mct family members
K1 developed three assays
K1 demonstrated selective engagement
K1 10 nm )
K1 intracellular lactic acid
K1 dependent cell line
K1 50 </ sub
K1 optimized compounds inhibit
K1 optimized compounds
K1 lactic acid
K1 therapeutic target
K1 therapeutic approach
K1 taken together
K1 readily amenable
K1 pharmacokinetic properties
K1 parent molecule
K1 orthogonal assay
K1 good physical
K1 glycolytic shutdown
K1 differential expression
K1 data demonstrate
K1 confocal microscopy
K1 cellular system
K1 cell growth
K1 cell chemoproteomics
K1 based screen
JF https://figshare.com/articles/dataset/Chemical_Biology_Approaches_Confirm_MCT4_as_the_Therapeutic_Target_of_a_Cellular_Optimized_Hit/21821532
LK http://dx.doi.org/https://doi.org/10.1021/acschembio.2c00666.s003
DO https://doi.org/10.1021/acschembio.2c00666.s003
SF ELIB - SuUB Bremen

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