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Anticancer Properties of Hexosamine Analogs Designed to Att..:
Christopher T. Saeui (4432354)
;
Sagar R. Shah (5318054)
;
Beatriz I. Fernandez-Gil (14375697)
...
https://figshare.com/articles/journal_contribution/Anticancer_Properties_of_Hexosamine_Analogs_Designed_to_Attenuate_Metabolic_Flux_through_the_Hexosamine_Biosynthetic_Pathway/21861762. , 2023
Link:
https://doi.org/10.1021/acschembio.2c00784.s001
RT Journal T1
Anticancer Properties of Hexosamine Analogs Designed to Attenuate Metabolic Flux through the Hexosamine Biosynthetic Pathway
UL https://suche.suub.uni-bremen.de/peid=base-ftunivfreestate:oai:figshare.com:article_21861762&Exemplar=1&LAN=DE A1 Christopher T. Saeui (4432354) A1 Sagar R. Shah (5318054) A1 Beatriz I. Fernandez-Gil (14375697) A1 Cissy Zhang (13766053) A1 Christian Agatemor (1488979) A1 Kris Dammen-Brower (14375700) A1 Mohit P. Mathew (14375703) A1 Matthew Buettner (14375706) A1 Prateek Gowda (5318051) A1 Pratik Khare (14375709) A1 Andrea Otamendi-Lopez (14375712) A1 Shuang Yang (64650) A1 Hui Zhang (7197) A1 Anne Le (266801) A1 Alfredo Quinoñes-Hinojosa (14375715) A1 Kevin J. Yarema (104690) YR 2023 K1 Biochemistry K1 Cell Biology K1 Genetics K1 Physiology K1 Pharmacology K1 Cancer K1 Inorganic Chemistry K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 targeted metabolomics analysis K1 nucleotide precursor biosynthesis K1 new therapeutic approach K1 hexosamine biosynthetic pathway K1 growth inhibitory effects K1 drives multiple facets K1 animals tolerated 5 K1 amino acid pools K1 increased metabolic flux K1 attenuate metabolic flux K1 regulated oncogenic metabolites K1 fold higher levels K1 hexosamine analogs designed K1 4 </ sub K1 gbm cells showed K1 reduce flux K1 oncogenic properties K1 vivo </ K1 reduced levels K1 endogenous levels K1 universal feature K1 study showed K1 salvage mechanisms K1 safely normalize K1 reduced proliferation K1 potent oncometabolite K1 neoplastic cells K1 including maintenance K1 important facet K1 glycan production K1 global disruption K1 glioblastoma multiform K1 gbm cells K1 concomitant decreases K1 anticancer properties K1 >- acetylglucosamine JF https://figshare.com/articles/journal_contribution/Anticancer_Properties_of_Hexosamine_Analogs_Designed_to_Attenuate_Metabolic_Flux_through_the_Hexosamine_Biosynthetic_Pathway/21861762 LK http://dx.doi.org/https://doi.org/10.1021/acschembio.2c00784.s001 DO https://doi.org/10.1021/acschembio.2c00784.s001 SF ELIB - SuUB Bremen
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