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Enabling Genetic Code Expansion and Peptide Macrocyclizatio..:

Sabrina E. Iskandar (14381196) ; Jarrett M. Pelton (14094740) ; Elizaveta T. Wick (14381199)...
https://figshare.com/articles/journal_contribution/Enabling_Genetic_Code_Expansion_and_Peptide_Macrocyclization_in_mRNA_Display_via_a_Promiscuous_Orthogonal_Aminoacyl-tRNA_Synthetase/21867693. , 2023

Link: https://doi.org/10.1021/jacs.2c11294.s001

RT Journal
T1 <Title>Enabling Genetic Code Expansion and Peptide Macrocyclization in mRNA Display via a Promiscuous Orthogonal Aminoacyl-tRNA Synthetase</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftunivfreestate:oai:figshare.com:article_21867693&Exemplar=1&LAN=DE
				
A1 Sabrina E. Iskandar (14381196)
A1 Jarrett M. Pelton (14094740)
A1 Elizaveta T. Wick (14381199)
A1 Derek L. Bolhuis (9761797)
A1 Albert S. Baldwin (13202391)
A1 Michael J. Emanuele (3260187)
A1 Nicholas G. Brown (1350612)
A1 Albert A. Bowers (1635184)
YR 2023
K1 Biophysics
K1 Biochemistry
K1 Molecular Biology
K1 Pharmacology
K1 Inorganic Chemistry
K1 Computational Biology
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 therapeutic protein targets
K1 pyridine – thiazoline
K1 pyr – thn
K1 provide structural novelty
K1 potent macrocyclic binder
K1 exhibits good selectivity
K1 >- cyanopyridylalanine (<
K1 >- cnpyra )
K1 mrna display via
K1 heterocycle forming macrocyclization
K1 deubiquitinase usp15 yielded
K1 mrna display libraries
K1 promiscuous orthogonal aminoacyl
K1 mrna display
K1 orthogonal aminoacyl
K1 display libraries
K1 >- cnf
K1 promiscuous ors
K1 work exemplifies
K1 vitro </
K1 usps )
K1 trna synthetases
K1 specific proteases
K1 relatively underexplored
K1 proven utility
K1 peptide macrocyclization
K1 p </
K1 novel substrate
K1 continually needed
K1 close homologues
K1 chemical diversity
K1 based selections
K1 amber codons
JF https://figshare.com/articles/journal_contribution/Enabling_Genetic_Code_Expansion_and_Peptide_Macrocyclization_in_mRNA_Display_via_a_Promiscuous_Orthogonal_Aminoacyl-tRNA_Synthetase/21867693
LK http://dx.doi.org/https://doi.org/10.1021/jacs.2c11294.s001
DO https://doi.org/10.1021/jacs.2c11294.s001
SF ELIB - SuUB Bremen

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