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Discovery and Hit-to-Lead Optimization of Benzothiazole Sca..:

Andrej Emanuel Cotman (5203904) ; Martina Durcik (8648943) ; Davide Benedetto Tiz (10499510)...
https://figshare.com/articles/dataset/Discovery_and_Hit-to-Lead_Optimization_of_Benzothiazole_Scaffold-Based_DNA_Gyrase_Inhibitors_with_Potent_Activity_against_Acinetobacter_baumannii_and_Pseudomonas_aeruginosa/21893089. , 2023

Link: https://doi.org/10.1021/acs.jmedchem.2c01597.s002

RT Journal
T1 <Title>Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftunivfreestate:oai:figshare.com:article_21893089&Exemplar=1&LAN=DE
				
A1 Andrej Emanuel Cotman (5203904)
A1 Martina Durcik (8648943)
A1 Davide Benedetto Tiz (10499510)
A1 Federica Fulgheri (10499513)
A1 Daniela Secci (1456555)
A1 Maša Sterle (10499516)
A1 Štefan Možina (7827599)
A1 Žiga Skok (9526072)
A1 Nace Zidar (1550383)
A1 Anamarija Zega (145577)
A1 Janez Ilaš (1550377)
A1 Lucija Peterlin Mašič (14420614)
A1 Tihomir Tomašič (1550395)
A1 Diarmaid Hughes (55014)
A1 Douglas L. Huseby (5082230)
A1 Sha Cao (194620)
A1 Linnéa Garoff (14420617)
A1 Talía Berruga Fernández (14420620)
A1 Paraskevi Giachou (14420623)
A1 Lisa Crone (14420626)
A1 Ivailo Simoff (13298093)
A1 Richard Svensson (1294284)
A1 Bryndis Birnir (113570)
A1 Sergiy V. Korol (13999896)
A1 Zhe Jin (43692)
A1 Francisca Vicente (484392)
A1 Maria C. Ramos (9616038)
A1 Mercedes de la Cruz (484390)
A1 Björn Glinghammar (14420629)
A1 Lena Lenhammar (4004096)
A1 Sara R. Henderson (14420632)
A1 Julia E. A. Mundy (7140383)
A1 Anthony Maxwell (9506)
A1 Clare E. M. Stevenson (9526084)
A1 David M. Lawson (357139)
A1 Guido V. Janssen (14420635)
A1 Geert Jan Sterk (3832357)
A1 Danijel Kikelj (1550389)
YR 2023
K1 Biophysics
K1 Biochemistry
K1 Medicine
K1 Cell Biology
K1 Pharmacology
K1 Cancer
K1 Infectious Diseases
K1 Space Science
K1 Chemical Sciences not elsewhere classified
K1 plasma free fraction
K1 ion channel liabilities
K1 fold decreased inhibition
K1 escherichia coli gyrb24
K1 dna gyrase inhibitor
K1 human topoisomerase iiα
K1 fold improved inhibition
K1 aeruginosa gyrb24 revealed
K1 27 </ b
K1 1 </ b
K1 topoisomerase iv
K1 >)-< b
K1 retained anti
K1 resistant bacteria
K1 pseudomonas aeruginosa
K1 promising activity
K1 priority list
K1 potent activity
K1 optimization steps
K1 negative activity
K1 mitochondrial toxicity
K1 lead optimization
K1 gyrb subunit
K1 developed compounds
K1 cocrystal structures
K1 benzothiazole scaffold
K1 adme properties
JF https://figshare.com/articles/dataset/Discovery_and_Hit-to-Lead_Optimization_of_Benzothiazole_Scaffold-Based_DNA_Gyrase_Inhibitors_with_Potent_Activity_against_Acinetobacter_baumannii_and_Pseudomonas_aeruginosa/21893089
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.2c01597.s002
DO https://doi.org/10.1021/acs.jmedchem.2c01597.s002
SF ELIB - SuUB Bremen

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