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1 Ergebnisse
1
Discovery of Tumor-Targeted 6‑Methyl Substituted Pemetrexed..:
Krishna Kaku
;
Manasa P. Ravindra
;
Nian Tong
...
doi:10.1021/acsmedchemlett.3c00326.s001. , 2023
Link:
https://doi.org/10.1021/acsmedchemlett.3c00326.s001
RT Journal T1
Discovery of Tumor-Targeted 6‑Methyl Substituted Pemetrexed and Related Antifolates with Selective Loss of RFC Transport
UL https://suche.suub.uni-bremen.de/peid=base-ftunivoxfordfig:oai:figshare.com:article_24565057&Exemplar=1&LAN=DE A1 Krishna Kaku A1 Manasa P. Ravindra A1 Nian Tong A1 Shruti Choudhary A1 Xinxin Li A1 Jianming Yu A1 Mohammad Karim A1 Madelyn Brzezinski A1 Carrie O'Connor A1 Zhanjun Hou A1 Larry H. Matherly A1 Aleem Gangjee YR 2023 K1 Biophysics K1 Biochemistry K1 Genetics K1 Molecular Biology K1 Pharmacology K1 Evolutionary Biology K1 Developmental Biology K1 Cancer K1 Chemical Sciences not elsewhere classified K1 preserving antitumor efficacy K1 carbon metabolic vulnerabilities K1 coupled folate transporter K1 >] pyrimidine antifolates K1 de novo </ K1 rfc transport pemetrexed K1 4 </ b K1 related antifolates K1 including pemetrexed K1 folate receptors K1 targeted therapeutics K1 standing goal K1 rfc ) K1 pyrrole ring K1 purine biosynthesis K1 molecular modeling K1 modest impacts K1 methyl moiety K1 methyl group K1 cancer cells K1 bicyclic scaffold K1 abolished transport K1 3 -< JF doi:10.1021/acsmedchemlett.3c00326.s001 LK http://dx.doi.org/https://doi.org/10.1021/acsmedchemlett.3c00326.s001 DO https://doi.org/10.1021/acsmedchemlett.3c00326.s001 SF ELIB - SuUB Bremen
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