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1 Ergebnisse
1
Discovery of Novel 2,3-Dihydro‑1 H ‑indene-5-sulfonamide NL..:
Simin Sun
;
Zhuoyue Li
;
Chao Huang
...
doi:10.1021/acs.jmedchem.3c01511.s001. , 2023
Link:
https://doi.org/10.1021/acs.jmedchem.3c01511.s001
RT Journal T1
Discovery of Novel 2,3-Dihydro‑1 H ‑indene-5-sulfonamide NLRP3 Inflammasome Inhibitors Targeting Colon as a Potential Therapy for Colitis
UL https://suche.suub.uni-bremen.de/peid=base-ftunivoxfordfig:oai:figshare.com:article_24667849&Exemplar=1&LAN=DE A1 Simin Sun A1 Zhuoyue Li A1 Chao Huang A1 Jinyu Liu A1 Qixin Yu A1 Xiaolin Jiang A1 Kairui Yue A1 Jianchun Zhao A1 Tongqiang Xu A1 Yankai Liu A1 Xiaoyang Li A1 Chong Qin A1 Yuqi Jiang YR 2023 K1 Biochemistry K1 Microbiology K1 Cell Biology K1 Pharmacology K1 Biotechnology K1 Immunology K1 Cancer K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 inflammatory bowel disease K1 favorable safety profile K1 nlrp3 protein (< K1 mechanistic studies indicate K1 nlrp3 inflammasome inhibitors K1 15z </ b K1 induced colitis model K1 dihydro ‑ 1 K1 nlrp3 inflammasome K1 results indicate K1 vivo </ K1 k </ K1 h </ K1 sulfonamide analogues K1 specific inhibitor K1 related diseases K1 potential therapy K1 novel 2 K1 notable distribution K1 multiprotein complex K1 multiple inflammation K1 low toxicity K1 identified compound K1 great potential K1 crucial role K1 binds directly K1 >‑ indene K1 >- indene K1 13 μm JF doi:10.1021/acs.jmedchem.3c01511.s001 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.3c01511.s001 DO https://doi.org/10.1021/acs.jmedchem.3c01511.s001 SF ELIB - SuUB Bremen
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