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Predicted effects of tecovirimat on peak viral load (VL), t..:
Bach Tran Nguyen
;
Aurélien Marc
;
Clara Suñer
...
doi:10.1371/journal.pbio.3002249.g004. , 2023
Link:
https://doi.org/10.1371/journal.pbio.3002249.g004
RT Journal T1
Predicted effects of tecovirimat on peak viral load (VL), time to undetectable VL by qPCR, and by viral culture, for different dosing regimens and initiation time
UL https://suche.suub.uni-bremen.de/peid=base-ftunivoxfordfig:oai:figshare.com:article_24887455&Exemplar=1&LAN=DE A1 Bach Tran Nguyen A1 Aurélien Marc A1 Clara Suñer A1 Michael Marks A1 Maria Ubals A1 Águeda Hernández-Rodríguez A1 María Ángeles Melendez A1 Dennis E. Hruby A1 Andrew T. Russo A1 France Mentré A1 Oriol Mitjà A1 Douglas W. Grosenbach A1 Jérémie Guedj YR 2023 K1 Medicine K1 Microbiology K1 Molecular Biology K1 Pharmacology K1 Biotechnology K1 Evolutionary Biology K1 Immunology K1 Cancer K1 Mental Health K1 Infectious Diseases K1 Virology K1 Computational Biology K1 Environmental Sciences not elsewhere classified K1 Biological Sciences not elsewhere classified K1 54 untreated patients K1 estimated mpox within K1 drug steady state K1 positive viral culture K1 pharmacological model developed K1 div >< p K1 viral dynamic model K1 characterize mpox kinetics K1 viral kinetics K1 mpox infection K1 drug administration K1 viral peak K1 mpox clearance K1 viral clearance K1 unique set K1 symptom onset K1 skin lesions K1 recommended doses K1 nonhuman primates K1 modeling framework K1 initiating treatment K1 infection day K1 infected cells K1 ideally starting K1 healthy volunteers K1 findings support K1 early administration K1 despite use K1 could reduce K1 antiviral effect K1 2022 outbreak K1 10 days K1 0 log JF doi:10.1371/journal.pbio.3002249.g004 LK http://dx.doi.org/https://doi.org/10.1371/journal.pbio.3002249.g004 DO https://doi.org/10.1371/journal.pbio.3002249.g004 SF ELIB - SuUB Bremen
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