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Discovery of Quinolinone Hybrids as Dual Inhibitors of Acet..:
Shoaib Manzoor
;
Moustafa T. Gabr
;
Mohamed S. Nafie
...
doi:10.1021/acschemneuro.3c00588.s001. , 2023
Link:
https://doi.org/10.1021/acschemneuro.3c00588.s001
RT Journal T1
Discovery of Quinolinone Hybrids as Dual Inhibitors of Acetylcholinesterase and Aβ Aggregation for Alzheimer's Disease Therapy
UL https://suche.suub.uni-bremen.de/peid=base-ftunivoxfordfig:oai:figshare.com:article_24907548&Exemplar=1&LAN=DE A1 Shoaib Manzoor A1 Moustafa T. Gabr A1 Mohamed S. Nafie A1 Md Kausar Raza A1 Ashma Khan A1 Shahid M. Nayeem A1 Reem K. Arafa A1 Nasimul Hoda YR 2023 K1 Biophysics K1 Biochemistry K1 Neuroscience K1 Pharmacology K1 Biotechnology K1 Cancer K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 sy5y cells incubated K1 immunohistochemistry investigation revealed K1 blood investigation illustrated K1 93 ± 0 K1 72 ± 0 K1 42 ± 0 K1 29 ± 0 K1 identify efficient therapeutics K1 am16 )</ b K1 am5 </ b K1 am10 </ b K1 50 </ sub K1 42 </ sub K1 dependent inhibitory profiles K1 inhibited ache activity K1 vivo </ K1 inhibitory activity K1 multitargeted therapeutics K1 dependent screening K1 protective activity K1 antioxidant activity K1 structural optimization K1 sod activities K1 retaining hematological K1 quinolinone hybrids K1 promising strategy K1 normal level K1 neuroprotective properties K1 neurological disorders K1 multitargeted ligands K1 induced neurotoxicity K1 increasing gsh K1 giving half K1 dual inhibitors K1 demonstrated concentration K1 assay confirmed K1 alzheimer ' K1 3 μm K1 18 μm K1 10 μm JF doi:10.1021/acschemneuro.3c00588.s001 LK http://dx.doi.org/https://doi.org/10.1021/acschemneuro.3c00588.s001 DO https://doi.org/10.1021/acschemneuro.3c00588.s001 SF ELIB - SuUB Bremen
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