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PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo De..:

Michael Berlin ; Jennifer Cantley ; Mark Bookbinder...
doi:10.1021/acs.jmedchem.3c01781.s001. , 2024

Link: https://doi.org/10.1021/acs.jmedchem.3c01781.s001

RT Journal
T1 <Title>PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftunivoxfordfig:oai:figshare.com:article_24949319&Exemplar=1&LAN=DE
				
A1 Michael Berlin
A1 Jennifer Cantley
A1 Mark Bookbinder
A1 Elizabeth Bortolon
A1 Fabio Broccatelli
A1 Greg Cadelina
A1 Emily W. Chan
A1 Huifen Chen
A1 Xin Chen
A1 Yunxing Cheng
A1 Tommy K. Cheung
A1 Kim Davenport
A1 Dean DiNicola
A1 Debbie Gordon
A1 Brian D. Hamman
A1 Alicia Harbin
A1 Roy Haskell
A1 Mingtao He
A1 Alison J. Hole
A1 Thomas Januario
A1 Philip S. Kerry
A1 Stefan G. Koenig
A1 Limei Li
A1 Mark Merchant
A1 Inmaculada Pérez-Dorado
A1 Jennifer Pizzano
A1 Connor Quinn
A1 Christopher M. Rose
A1 Emma Rousseau
A1 Leofal Soto
A1 Leanna R. Staben
A1 Hongming Sun
A1 Qingping Tian
A1 Jing Wang
A1 Weifeng Wang
A1 Crystal S. Ye
A1 Xiaofen Ye
A1 Penghong Zhang
A1 Yuhui Zhou
A1 Robert Yauch
A1 Peter S. Dragovich
YR 2024
K1 Biophysics
K1 Biochemistry
K1 Cell Biology
K1 Genetics
K1 Molecular Biology
K1 Immunology
K1 Cancer
K1 Computational Biology
K1 Chemical Sciences not elsewhere classified
K1 Physical Sciences not elsewhere classified
K1 Information Systems not elsewhere classified
K1 thus highly dependent
K1 pd analysis established
K1 also selectively impair
K1 >) also supported
K1 compounds identified protacs
K1 selectively degraded brm
K1 type calu6 line
K1 h1944 " brg1
K1 fold degradation selectivity
K1 protacs targeting brm
K1 also known
K1 brm protein
K1 brm (<
K1 vivo </
K1 sw1573 cell
K1 subsequent pk
K1 plau </
K1 mrna associated
K1 molecules exhibit
K1 latter system
K1 krt80 </
K1 intratumor quantitation
K1 experiments performed
K1 based experiments
K1 afford selective
JF doi:10.1021/acs.jmedchem.3c01781.s001
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.3c01781.s001
DO https://doi.org/10.1021/acs.jmedchem.3c01781.s001
SF ELIB - SuUB Bremen

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