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Identification and Optimization of Small Molecule Pyrazolop..:

Liqi He ; Meng Yao Zhang ; Matthew Cox...
doi:10.1021/acsmedchemlett.3c00456.s001. , 2024

Link: https://doi.org/10.1021/acsmedchemlett.3c00456.s001

RT Journal
T1 <Title>Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftunivoxfordfig:oai:figshare.com:article_24968292&Exemplar=1&LAN=DE
				
A1 Liqi He
A1 Meng Yao Zhang
A1 Matthew Cox
A1 Qian Zhang
A1 Andrew F. Donnell
A1 Yong Zhang
A1 Christine Tarby
A1 Patrice Gill
A1 Murugaiah A. M. Subbaiah
A1 Thangeswaran Ramar
A1 Maheswara Reddy
A1 Vijaya Puttapaka
A1 Yi-Xin Li
A1 Prasanna Sivaprakasam
A1 David Critton
A1 Dawn Mulligan
A1 Chunshan Xie
A1 Radha Ramakrishnan
A1 Jignesh Nagar
A1 Shailesh Dudhgaonkar
A1 Anwar Murtaza
A1 Martins S. Oderinde
A1 Gary L. Schieven
A1 Arvind Mathur
A1 Ashvinikumar V. Gavai
A1 Gregory Vite
A1 Sanjeev Gangwar
A1 Yam B. Poudel
YR 2024
K1 Biochemistry
K1 Medicine
K1 Pharmacology
K1 Immunology
K1 Cancer
K1 Computational Biology
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 Physical Sciences not elsewhere classified
K1 synergistic antitumor activity
K1 promising therapeutic agents
K1 phenylpiperidine side chain
K1 gathered considerable interest
K1 novel tlr7 agonists
K1 adme properties culminated
K1 14 </ b
K1 vivo </
K1 like properties
K1 7 agonists
K1 suggesting opportunities
K1 pharmacodynamic profiles
K1 oncology therapies
K1 like receptor
K1 favorable drug
K1 demonstrated excellent
K1 cancer immunotherapy
K1 apd1 antibody
K1 additional refinement
JF doi:10.1021/acsmedchemlett.3c00456.s001
LK http://dx.doi.org/https://doi.org/10.1021/acsmedchemlett.3c00456.s001
DO https://doi.org/10.1021/acsmedchemlett.3c00456.s001
SF ELIB - SuUB Bremen

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