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Development of a Cost-Efficient Process Toward a Key Synthe..:

Christopher P. Ashcroft ; Alexander M. Berne ; Florian Blasberg...
doi:10.1021/acs.oprd.3c00477.s001. , 2024

Link: https://doi.org/10.1021/acs.oprd.3c00477.s001

RT Journal
T1 <Title>Development of a Cost-Efficient Process Toward a Key Synthetic Intermediate of the EZH2 Inhibitor PF-06821497</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftunivoxfordfig:oai:figshare.com:article_25290281&Exemplar=1&LAN=DE
				
A1 Christopher P. Ashcroft
A1 Alexander M. Berne
A1 Florian Blasberg
A1 Kelly Catlin
A1 Michael R. Collins
A1 Doug J. Critcher
A1 Jean-Nicolas Desrosiers
A1 Adam Goetz
A1 Cheryl Hayward
A1 Ricky A. Jones
A1 Michael J. Karmilowicz
A1 Nandell Keene
A1 Carlos A. Martinez
A1 Sebastien Monfette
A1 Sebastian David Pattavina
A1 Hahdi H. Perfect
A1 John A. Ragan
A1 Blake Rauschenberger
A1 Neal W. Sach
A1 Gemma Scotney
A1 Scott C. Sutton
A1 Courtney Talicska
A1 Steven J.R. Twiddle
A1 Jared Van Haitsma
A1 Richard Wisdom
YR 2024
K1 Biochemistry
K1 Genetics
K1 Pharmacology
K1 Ecology
K1 Infectious Diseases
K1 Space Science
K1 Environmental Sciences not elsewhere classified
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 targeted building block
K1 subsequent methylation followed
K1 key synthetic intermediate
K1 ezh2 inhibitor pf
K1 efficient process toward
K1 key intermediate
K1 efficient approach
K1 seven steps
K1 overall yield
K1 large scale
K1 kred process
K1 initially deployed
K1 finally identify
K1 enantioenriched alcohol
K1 desired oxetanyl
K1 carboxylation led
K1 50 kg
K1 28 %
JF doi:10.1021/acs.oprd.3c00477.s001
LK http://dx.doi.org/https://doi.org/10.1021/acs.oprd.3c00477.s001
DO https://doi.org/10.1021/acs.oprd.3c00477.s001
SF ELIB - SuUB Bremen

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