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De novo mutations disturb early brain development more freq..:

Itai, Toshiyuki ; Jia, Peilin ; Dai, Yulin...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  192 (2023)  3-4 - p. 62-70 , 2023
Link: https://doi.org/10.1002/ajmg.b.32932