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Homocysteine, rather than age of onset, is a better predict..:

Chen, Pao‐Huan ; Liu, Hsing‐Cheng ; Lu, Mong‐Liang...
International Journal of Geriatric Psychiatry.  34 (2019)  10 - p. 1473-1480 , 2019
Link: https://doi.org/10.1002/gps.5156