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Maternal plasma phospholipids are altered in trisomy 21 cas..:

Pinto, Joana ; Maciel, Elisabete ; Melo, Tânia S....
Rapid Communications in Mass Spectrometry.  28 (2014)  14 - p. 1635-1638 , 2014
Link: https://doi.org/10.1002/rcm.6941