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Bleeding is increased in amyloid precursor protein knockout..:

Mazinani, Nima ; Strilchuk, Amy W. ; Baylis, James R....
Research and Practice in Thrombosis and Haemostasis.  4 (2020)  5 - p. 823-828 , 2020
Link: https://doi.org/10.1002/rth2.12375