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Time for first antibiotic dose is not predictive for the ea..:

Bruns, A. H. W. ; Oosterheert, J. J. ; Hustinx, W. N. M....
European Journal of Clinical Microbiology & Infectious Diseases.  28 (2009)  8 - p. 913-919 , 2009
Link: https://doi.org/10.1007/s10096-009-0724-6