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Trp-16 is essential for the activity of α-galactosidase and..:

Zhu, Alex ; Monahan, Catherine ; Wang, Zhong-Kun
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology.  1297 (1996)  1 - p. 99-104 , 1996
Link: https://doi.org/10.1016/0167-4838(96)00108-2