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Cigarette smoking reduces human salivary eicosanoids:

Wu-Wang, C.Y. ; Wang, S.-L. ; Lim, C....
Prostaglandins, Leukotrienes and Essential Fatty Acids.  47 (1992)  2 - p. 101-104 , 1992
Link: https://doi.org/10.1016/0952-3278(92)90144-8