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Severely impaired respiratory chain causes multisystem apop..:

Indrieri, A. ; Van Rahden, V. ; Tiranti, V....
Biochimica et Biophysica Acta (BBA) - Bioenergetics.  1817 (2012)  - p. S157 , 2012
Link: https://doi.org/10.1016/j.bbabio.2012.06.411