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The key role of glutamate 172 in the mechanism of type II N..:

Sousa, Filipe M. ; Sena, Filipa V. ; Batista, Ana P....
Biochimica et Biophysica Acta (BBA) - Bioenergetics.  1858 (2017)  10 - p. 823-832 , 2017
Link: https://doi.org/10.1016/j.bbabio.2017.08.002