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Significantly increased fractions of transformed to total α..:

Jensen, Poul Erik H. ; Humle Jørgensen, Signe ; Datta, Pameli.
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.  1690 (2004)  3 - p. 203-207 , 2004
Link: https://doi.org/10.1016/j.bbadis.2004.06.010