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Extracellular histones activate autophagy and apoptosis via..:

Ibañez-Cabellos, José Santiago ; Aguado, Carmen ; Pérez-Cremades, Daniel...
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.  1864 (2018)  10 - p. 3234-3246 , 2018
Link: https://doi.org/10.1016/j.bbadis.2018.07.010