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Arginine 383 is a crucial residue in ABCG2 biogenesis:

Polgar, Orsolya ; Ediriwickrema, Lilangi S. ; Robey, Robert W....
Biochimica et Biophysica Acta (BBA) - Biomembranes.  1788 (2009)  7 - p. 1434-1443 , 2009
Link: https://doi.org/10.1016/j.bbamem.2009.04.016