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Membrane cholesterol is essential for triterpenoid saponin ..:

Smith, Wendy S. ; Baker, Ella J. ; Holmes, Suzanne E....
Biochimica et Biophysica Acta (BBA) - Biomembranes.  1859 (2017)  5 - p. 993-1007 , 2017
Link: https://doi.org/10.1016/j.bbamem.2017.02.013