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Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST)..:

Gerlt, John A. ; Bouvier, Jason T. ; Davidson, Daniel B....
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics.  1854 (2015)  8 - p. 1019-1037 , 2015
Link: https://doi.org/10.1016/j.bbapap.2015.04.015