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Human chromosome 21q22.2-qter carries a gene(s) responsible..:

Kazuki, Yasuhiro ; Kimura, Motoshi ; Nishigaki, Ryuichi...
Biochemical and Biophysical Research Communications.  317 (2004)  2 - p. 491-499 , 2004
Link: https://doi.org/10.1016/j.bbrc.2004.03.069