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Designing effective siRNAs with off-target control:

Snøve Jr., Ola ; Nedland, Magnar ; Fjeldstad, Ståle H....
Biochemical and Biophysical Research Communications.  325 (2004)  3 - p. 769-773 , 2004
Link: https://doi.org/10.1016/j.bbrc.2004.10.097