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Overexpressed proteins may act as mops removing their ligan..:

Breer, Katarzyna ; Wielgus-Kutrowska, Beata ; Girstun, Agnieszka...
Biochemical and Biophysical Research Communications.  391 (2010)  2 - p. 1203-1209 , 2010
Link: https://doi.org/10.1016/j.bbrc.2009.12.037