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The human LIS1 is downregulated in hepatocellular carcinoma..:

Xing, Zhen ; Tang, Xin ; Gao, Yuan...
Biochemical and Biophysical Research Communications.  409 (2011)  2 - p. 193-199 , 2011
Link: https://doi.org/10.1016/j.bbrc.2011.04.117