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Activation of p53–p21 is closely associated with the acquis..:

Kim, Mi Ra ; Chang, Hyo Won ; Nam, Hae Yun...
Biochemical and Biophysical Research Communications.  418 (2012)  2 - p. 260-266 , 2012
Link: https://doi.org/10.1016/j.bbrc.2012.01.007