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HBx affects CUL4–DDB1 function in both positive and negativ..:

Guo, Liandi ; Wang, Xiaobo ; Ren, Laifeng...
Biochemical and Biophysical Research Communications.  450 (2014)  4 - p. 1492-1497 , 2014
Link: https://doi.org/10.1016/j.bbrc.2014.07.019