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An alpha-adrenergic agonist protects hearts by inducing Akt..:

Nakaoka, Mikihiko ; Iwai-Kanai, Eri ; Katamura, Maki...
Biochemical and Biophysical Research Communications.  456 (2015)  1 - p. 250-256 , 2015
Link: https://doi.org/10.1016/j.bbrc.2014.11.067