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18O labeling on Ser45 but not on Ser35 supports the coopera..:

Sulbarán, Guidenn ; Biasutto, Antonio ; Méndez, Franklin...
Biochemical and Biophysical Research Communications.  524 (2020)  1 - p. 198-204 , 2020
Link: https://doi.org/10.1016/j.bbrc.2020.01.044