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Possible involvement of hydroxyl radical on the stimulation..:

Shimizu, Shunichi ; Ishii, Masakazu ; Miyasaka, Yoshiyuki...
The International Journal of Biochemistry & Cell Biology.  37 (2005)  4 - p. 864-875 , 2005
Link: https://doi.org/10.1016/j.biocel.2004.11.003